Multiregression Analysis of Model Parameter as Independent Variable
| Mean annual MMSE decline | Mean annual ADAS-Cog decline | Mean annual ADAS-Mod decline | ||||||||||
| Model | B | SE | β | P | B | SE | β | P | B | SE | β | P |
| Age | 0.01 | 0.01 | 0.04 | 0.30 | 0.01 | 0.01 | 0.02 | 0.62 | 0.04 | 0.02 | 0.07 | 0.05 |
| ApoE4 | −0.34 | 0.20 | −0.06 | 0.09 | 0.22 | 0.21 | 0.04 | 0.30 | 0.69 | 0.30 | 0.09 | 0.02 |
| Diagnostic group (control, MCI, AD) | −1.16 | 0.14 | −0.30 | 0.00 | 1.52 | 0.14 | 0.37 | 0.00 | 1.16 | 0.21 | 0.20 | 0.00 |
| Sex | −0.09 | 0.20 | −0.02 | 0.65 | 0.61 | 0.20 | 0.10 | 0.00 | 0.64 | 0.29 | 0.08 | 0.03 |
| TSOP genotype (Thr/Thr, Ala/Thr, Ala/Ala) | 0.26 | 0.15 | 0.06 | 0.08 | −0.18 | 0.15 | −0.04 | 0.24 | 0.07 | 0.22 | 0.01 | 0.75 |
B = unstandardized coefficient; β = standardized coefficient.