Characteristics of Study Cohort
Patient characteristic (n = 73) | Median or absolute number* |
Age (y) | 52 (IQR, 24) |
Sex | |
Female | 37 (51%) |
Male | 36 (49%) |
Site | |
Head and neck | 3 (4%) |
Chest and trunk | 7 (10%) |
Abdomen and retroperitoneum | 36 (49%) |
Extremities | 27 (37%) |
Histology | |
Angiosarcoma | 6 (8%) |
Leiomyosarcoma | 13 (18%) |
Liposarcoma | 13 (18%) |
MPNST | 6 (8%) |
Synovial sarcoma | 4 (5%) |
Pleomorphic undifferentiated sarcoma | 15 (21%) |
Other | 16 (22%) |
FNCLCC grade | |
1 | 1 (1%) |
2 | 22 (30%) |
3 | 50 (69%) |
Stage | |
Recurrent tumor | 18 (25%) |
Primary tumor | 55 (75%) |
Radiotherapy | |
Yes | 30 (41%) |
No | 43 (59%) |
Surgery | |
After chemotherapy | 34 (47%) |
Before chemotherapy | 27 (37%) |
No surgery | 12 (16%) |
Chemotherapy | |
AI | 66 (90%) |
EDIC | 3 (4%) |
Mini-ICE | 4 (6%) |
Progression (events) | |
Local | 27 (37%) |
Distant | 24 (33%) |
Local plus distant | 37 (51%) |
Deaths | 19 (26%) |
Time to event overall (mo) | 15.3 (IQR, 17.7) |
Overall survival (mo) | 22.2 (IQR, 17.3) |
Time of follow-up (mo) | 22.2 (IQR, 17.3) |
No. of therapy courses between PET scans | 3 (IQR, 2) |
No. of therapy courses from second PET to surgery | 1 (IQR, 2) |
* Data are median, with IQR in parentheses, or absolute number (with % in parentheses).
MPNST = malignant peripheral nerve sheath tumor; FNCLCC = French Fédération Nationale des Centers de Lutte Contre le Cancer.