TABLE 2

Demographic Characteristics and Clinical Ratings of Cognitively Normal APOE4 Carrier and Noncarrier Groups

Mean ± SD for:
CharacteristicAPOE4 carriers (n = 30*)APOE4 noncarriers (n = 84†)P
Baseline age (y)77.0 ± 5.477.7 ± 6.30.58
Sex (no. of men/women)17/1347/370.95
Education (y)15.9 ± 3.016.6 ± 2.80.25
Follow-up duration (mo)24.4 ± 2.323.6 ± 1.20.04
Baseline MMSE score28.7 ± 1.329.2 ± 1.20.07
24-mo MMSE score decrease−0.2 ± 1.8−0.5 ± 1.40.28
Baseline ADAS-Cog13 rating10.9 ± 4.69.0 ± 4.60.07
24-mo ADAS-Cog13 rating increase0.7 ± 4.4−0.02 ± 3.20.33
Baseline CDR-SB score0.1 ± 0.4−0.03 ± 0.70.32
24-mo CDR-SB score increase0.1 ± 0.60.3 ± 1.20.56

  • ↵* Scores on MMSE and ratings on ADAS-Cog13 were not available for 1 and 4 of these subjects, respectively.

  • ↵† Scores on MMSE and ratings on ADAS-Cog13 were not available for 4 and 5 of these subjects, respectively.