TABLE 2

Biodistribution of 86Y-4 in Mice (%ID/g)

Tissue1 h2 h5 h24 h
Blood0.5 ± 0.20.1 ± 0.10.0 ± 0.00.0 ± 0.0
Heart0.3 ± 0.10.1 ± 0.00.0 ± 0.00.0 ± 0.0
Lung1.1 ± 0.20.3 ± 0.10.1 ± 0.00.0 ± 0.0
Liver0.2 ± 0.10.1 ± 0.00.1 ± 0.00.0 ± 0.0
Spleen5.1 ± 1.41.3 ± 0.50.2 ± 0.10.0 ± 0.0
Kidney245.0 ± 9.0123.0 ± 4823.0 ± 9.71.5 ± 0.7
Muscle0.5 ± 0.40.1 ± 0.10.1 ± 0.10.0 ± 0.0
Small intestines0.2 ± 0.00.1 ± 0.00.0 ± 0.00.0 ± 0.0
Large intestines0.3 ± 0.10.1 ± 0.00.1 ± 0.00.0 ± 0.0
Bladder1.5 ± 0.812.6 ± 12.53.6 ± 1.0.2 ± 0.2
PC-3 PIP29.0 ± 8.721.6 ± 3.615.7 ± 1.75.9 ± 0.8
PC-3 flu0.3 ± 0.10.1 ± 0.00.1 ± 0.00.0 ± 0.0
PIP to flu89164156229
PIP to blood551986242,352
PIP to muscle541401911,046