68Ga-P03034 | 68Ga-P04158 | 68Ga-Z02090 | ||||
Tissue (%ID/g) | Control (n = 5) | Blocked (n = 4) | Control (n = 5) | Blocked (n = 4) | Control (n = 5) | Blocked (n = 4) |
Blood | 0.46 ± 0.34 | 0.23 ± 0.06 | 1.12 ± 0.37 | 1.53 ± 0.54 | 0.50 ± 0.13 | 0.62 ± 0.09 |
Fat | 0.11 ± 0.10 | 0.08 ± 0.08 | 0.18 ± 0.04 | 0.20 ± 0.12 | 0.07 ± 0.02 | 0.09 ± 0.00 |
Testes | 0.16 ± 0.10 | 0.12 ± 0.11 | 0.31 ± 0.08 | 0.34 ± 0.12 | 0.15 ± 0.06 | 0.20 ± 0.04 |
Large intestine | 0.19 ± 0.12 | 0.14 ± 0.02 | 0.41 ± 0.15 | 0.46 ± 0.17 | 0.20 ± 0.05 | 0.20 ± 0.03 |
Small intestine | 0.22 ± 0.26 | 0.13 ± 0.07 | 0.47 ± 0.05 | 0.62 ± 0.18 | 0.24 ± 0.07 | 0.45 ± 0.17 |
Spleen | 0.23 ± 0.17 | 0.11 ± 0.03 | 0.46 ± 0.12 | 0.51 ± 0.13 | 0.31 ± 0.10 | 0.34 ± 0.05 |
Liver | 0.18 ± 0.10 | 0.14 ± 0.05 | 0.72 ± 0.11 | 0.79 ± 0.18 | 0.32 ± 0.07 | 0.29 ± 0.03 |
Pancreas | 0.07 ± 0.08 | 0.06 ± 0.01 | 0.26 ± 0.03 | 0.30 ± 0.12 | 0.11 ± 0.02 | 0.13 ± 0.02 |
Adrenal glands | 0.15 ± 0.16 | 0.15 ± 0.17 | 1.19 ± 0.78 | 0.68 ± 0.44 | 0.37 ± 0.19 | 0.27 ± 0.09 |
Kidney | 4.50 ± 2.17 | 3.19 ± 0.72 | 69.2 ± 7.39 | 52.7 ± 2.85 | 50.1 ± 9.68 | 47.9 ± 7.78 |
Lungs | 0.53 ± 0.38 | 0.20 ± 0.05 | 0.89 ± 0.17 | 1.27 ± 0.40 | 0.48 ± 0.09 | 0.52 ± 0.04 |
Heart | 0.15 ± 0.07 | 0.09 ± 0.02 | 0.52 ± 0.13 | 0.59 ± 0.22 | 0.21 ± 0.06 | 0.27 ± 0.04 |
B1R− tumor | 0.36 ± 0.09 | 0.25 ± 0.09 | 0.61 ± 0.21 | 0.67 ± 0.21 | 0.53 ± 0.18 | 0.45 ± 0.11 |
B1R+ tumor | 2.17 ± 0.49 | 0.41 ± 0.08* | 19.6 ± 4.50 | 1.44 ± 0.12* | 14.4 ± 1.63 | 0.85 ± 0.17* |
Muscle | 0.13 ± 0.13 | 0.06 ± 0.01 | 0.30 ± 0.05 | 0.45 ± 0.26 | 0.12 ± 0.04 | 0.13 ± 0.02 |
Bone | 0.10 ± 0.10 | 0.09 ± 0.03 | 0.45 ± 0.03 | 0.50 ± 0.17 | 0.22 ± 0.09 | 0.26 ± 0.07 |
Brain | 0.01 ± 0.01 | 0.02 ± 0.02 | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.01 ± 0.01 | 0.02 ± 0.01 |
B1R+ tumor to B1R− tumor | 6.23 ± 1.69 | 1.85 ± 0.88† | 34.5 ± 10.5 | 2.33 ± 0.76* | 29.3 ± 9.68 | 2.04 ± 0.79* |
B1R+ tumor to blood | 5.72 ± 2.20 | 1.92 ± 0.58† | 19.2 ± 8.21 | 1.05 ± 0.43† | 29.9 ± 5.58 | 1.37 ± 0.23* |
B1R+ tumor to muscle | 25.5 ± 13.1 | 6.61 ± 1.54‡ | 66.1 ± 17.0 | 4.36 ± 2.96* | 124 ± 28.1 | 6.85 ± 1.59* |
B1R+ tumor to liver | 14.6 ± 6.16 | 3.10 ± 1.05† | 26.9 ± 2.93 | 1.90 ± 0.51* | 45.6 ± 5.86 | 3.09 ± 0.40* |
B1R+ tumor to kidney | 0.54 ± 0.18 | 0.13 ± 0.04† | 0.28 ± 0.05 | 0.03 ± 0.00* | 0.30 ± 0.07 | 0.02 ± 0.00* |
Significance of differences between control and blocked groups: *P < 0.001; †P < 0.01; ‡P < 0.05.