TABLE 1

Injected Radioactivity Dose, Yohimbine Mass, and CYP2D6 Status

SubjectMBqYohimbine (nmol)CYP2D6
164130.31 × 2 (F)
24414.64 × 1 (M)
363571 × 4 (M)
471521.44 × 4 (N)
550711.22 × 5 (M)
6169112 × 2 (F)
  • F, M, and N = fast, moderate, and nonmetabolizers, respectively, of 11C-yohimbine.