Subjects’ Characteristics
| Characteristic | AD patients | HC1 (PET) | HC2 (fMRI) | P (AD vs. HC1/AD vs. HC2) |
| n | 15 | 15 | 17 | |
| Women (%) | 40% | 67% | 59% | 0.272/0.479, Fisher exact |
| Mean age (y) | 65.00 ± 8.80 | 64.60 ± 5.77 | 65.05 ± 5.62 | 0.884/0.982 |
| MMSE | ||||
| Baseline | 23.80 ± 3.34 | 29.27 ± 0.70 | 29.18 ± 0.81 | 0.000/0.000 |
| Follow up | 17.93 ± 8.44 | 29.27 ± 0.70 | 29.18 ± 0.81 | 0.000/0.000 |
| CDR (global) | ||||
| Baseline | 0.50 (Median) | 0.00 (Median) | 0.00 (Median) | 0.000/0.000, Mann–Whitney U |
| 0.50 (Range) | 0.00 (Range) | 0.50 (Range) | ||
| Follow up | 1.00 (Median) | 0.00 (Median) | 0.00 (Median) | 0.000/0.000, Mann–Whitney U |
| 1.50 (Range) | 0.00 (Range) | 0.50 (Range) | ||
| APOE ε4 (+/−) | 10/5 | 8/7 | 7/10 | 0.710/0.462, Fisher exact |
| Education (y) | 8.93 ± 1.58 | 9.79 ± 1.72 | 9.53 ± 1.55 | 0.175/0.303 |
Data are mean ± SD. P values are results from t tests, unless otherwise noted.
APOE ε4 (+/−) = carrier/noncarrier of APO-E ε4 allele.