TABLE 2

Diagnostic Value of 18F-FDG PET and 18F-FDG PET/CT for Detection of Bone Marrow Involvement in Pediatric Patients with Malignant Lymphoma

StudyType of diseasePatients (n)BMB sensitivityBMB specificityPET sensitivity in BM evaluationPET specificity in BM evaluation
Agrawal (35)HL3862.5%100%87.5%100%
Cheng (36)HL&NHL5454%100%92%100%
Purz (37)HL175NANA100%77.3%*, 92.2%†, 98.5%‡

  • ↵* Confirmed only by positive BMB.

  • ↵† Confirmed by BMB or multifocality.

  • ↵‡ Confirmed by BMB, multifocality, or chemotherapy response.

  • BM = bone marrow; BMB = bone marrow biopsy; NA = data not available.