Diagnostic Value of 18F-FDG PET and 18F-FDG PET/CT for Detection of Pulmonary Metastases in Pediatric Patients with Malignant Sarcomas
| Study | Type of disease | Patients (n) | Timing of PET/CT | Sensitivity | Specificity | PPV | NPV |
| Völker (78) | OS, ES, RMS | 46 | Initial staging | 25% | NA | 100% | NA |
| London (3) | OS, ES | 41 | All | 80.0% | 95.8% | 80% | 95.8% |
| Cistaro (134) | OS, ES, ChS | 18 | Restaging | 90.3% | 93.8% | 91.0% | 93.3% |
PPV = positive predictive value; NPV = negative predictive value; OS = osteosarcoma; ES = Ewing sarcoma; RMS = rhabdomyosarcoma; NA = data not available; ChS = chondrosarcoma.