TABLE 2

Observed Versus Expected Numbers of Deaths in Each TNM Stage for Various Follow-up Periods

		Value for stage^*:
Follow-up	Parameter	I (1,577)	II (306)	III (300)	IVA (95)	IVC (150)
5 y	O	13	11	19	6	38
	E	27.0	11.5	13.7	5.4	14.0
	SMR for O/E (95% CI)	0.48 (0.26–0.89)	0.96 (0.49–1.86)	1.39 (0.84–2.31)	1.11 (0.46–2.69)	2.72 (1.90–3.91)
	P	0.007	0.887	0.149	0.801	<0.001
10 y	O	34	24	24	10	56
	E	51.3	22.7	24.7	9.7	22.0
	SMR for O/E (95% CI)	0.66 (0.45–0.97)	1.06 (0.67–1.66)	0.97 (0.62–1.53)	1.03 (0.51–2.06)	2.54 (1.89–3.42)
	P	0.016	0.786	0.885	0.924	<0.001
15 y	O	45	32	29	12	69
	E	69.6	31.6	31.9	11.2	26.6
	SMR for O/E (95% CI)	0.65 (0.46–0.90)	1.01 (0.68–1.50)	0.91 (0.60–1.38)	1.07 (0.57–2.03)	2.59 (1.98–3.39)
	P	0.003	0.936	0.613	0.810	<0.001
20 y	O	51	37	32	14	73
	E	79.9	36.9	35.4	12.0	29.1
	SMR for O/E (95% CI)	0.64 (0.47–0.87)	1.0 (0.7–1.45)	0.9 (0.61–1.34)	1.16 (0.65–2.10)	2.51 (1.93–3.26)
	P	0.001	0.983	0.571	0.569	<0.001
Maximum	O	52	38	33	14	75
	E	84.7	40.3	35.8	12.1	30.7
	SMR for O/E (95% CI)	0.61 (0.45–0.84)	0.94 (0.66–1.35)	0.92 (0.63–1.36)	1.16 (0.64–2.10)	2.45 (1.89–3.17)
	P	<0.001	0.713	0.640	0.576	<0.001

↵* Values in parentheses are numbers of patients.
O = observed number of deaths in population of patients with DTC; E = expected number of deaths in matched population.