TABLE 4

Clinicopathologic Characteristics and Clinical Outcomes of OSCC Patients Who Had Positive Findings on Preradiotherapy/CCRT PET/CT Imaging

			Prognostic scoring system
Case no.	Primary cancer site	Primary staging	Extracapsular spread	Lymphatic invasion	Score	Pre-RT/CCRT PET findings	Evidence	Adjuvant treatment modification	Outcomes	Follow-up (mo)
1	Left tongue	pT2N0M0	N	N	0	Local, LN (left N3)	Imaging follow-up	Curative CCRT^*	NED	49
2	Right tongue	pT4aN1M0	N	N	0	LN (right, level IV)	Tissue proven	Curative CCRT^†	NED	24
3	Right bucca	pT4aN0M0	N	N	0	Local	Imaging follow-up	Curative CCRT^*	NED	42
4	Left bucca	pT2N0M0	N	N	0	Lung	Imaging follow-up	Palliation	DOD	4
5	Left tongue	pT3N0M0	N	N	0	Local	Imaging follow-up	Curative CCRT^*	NED	34
6	Left bucca	pT4aN0M0	N	N	0	Local	Imaging follow-up	Curative CCRT^*	DOD	12
7	Right tongue	pT4aN2bM0	P	N	1	LN (left, level V)	Tissue roven	Curative CCRT^†	NED	47
8	Right bucca	pT2N2bM0	P	N	1	Local	Imaging follow-up	Curative CCRT^*	NED	26
9	Right tongue	pT4aN2cM0	P	N	1	LN (left, level IV)	Imaging Follow-up	Curative CCRT^†	DOD	13
10	Right tongue	pT2N2bM0	P	N	1	LN (left, level I, II, III)	Tissue proven	Curative CCRT^†	DOD	16
11	Left tongue	pT2N2bM0	P	N	1	LN (right, level III, V)	Imaging follow-up	Curative CCRT^†	NED	31
12	Right tongue	pT2N2cM0	P	N	1	LN (right, level III, IV)	Tissue proven	Curative CCRT^†	DOD	9
13	Right bucca	pT4aN2bM0	P	N	1	Lung	Imaging follow-up	Palliation	DOD	2
14	Left bucca	pT3N2bM0	P	N	1	Local, LN (left, level III), lung	Tissue proven	Palliation	DOD	5
15	Left mouth floor	pT4aN2bM0	P	N	1	Lung	Imaging follow-up	Palliation	DOD	3
16	Right alveolar ridge	pT4aN1M0	P	N	1	Local	Imaging follow-up	Curative CCRT^*	DOD	8
17	Right bucca	pT4aN2bM0	P	P	2	Local, LN (left, level V and parotid)	Tissue proven	Curative CCRT^†	DOD	4
18	Right bucca	pT4aN2bM0	P	P	2	LN (left, level IV and parotid)	Imaging follow-up	Curative CCRT^‡	DOD	9
19	Right alveolar ridge	pT3N2bM0	P	P	2	LN (right, level V and left, parotid)	Tissue proven	Curative CCRT^†	DOD	6
20	Left retromolar trigone	pT4aN0M0	N	N	0	Lung score 3^§	Imaging follow-up	Radiotherapy	NED	36
21	Right buccal	pT4aN0M0	N	N	0	Lung score 3^§	Imaging follow-up	Radiotherapy	NED	33
22	Right retromolar trigone	pT2N0M0	N	N	0	Local (right mandible, score 3^§)	Tissue-proven negative	Radiotherapy	NED	60
23	Left tongue	pT2N2bM0	N	P	1	LN (right, level II, score 3^§), lung, score 3^§	Tissue-proven (LN) negative	Curative CCRT^†	DOD (pleural effusion)	8
24	Left alveolar ridge	pT4aN0M0	N	N	0	Local (left upper gum, score 3^§)	Tissue-proven negative	Radiotherapy	NED	33
25	Left tongue	pT2N2bM0	P	N	1	LN (right level III, V, score 3^§)	Tissue-proven negative	Curative CCRT^†	NED	32
26	Right alveolar ridge	pT4aN1M0	N	N	0	LN (right, level V, left SCF, both scores 3^§)	Tissue-proven negative	Curative CCRT^†	NED	28

↵* Change RT dose; ^†Change RT dose and field; ^‡Change field; ^§PET/CT score.
ES = extracapsular spread; LI = lymphatic invasion; RT = radiotherapy; N = negative; LN = lymph node; P = positive; NED = no evidence of disease, DOD = died of disease; SCF = supraclavicular fossa.