Experimental Details and Tissue Characterization
Subject* | Imaging day | PGL | 18F-FDG (MBq) | 111In (MBq) | 111In LE | 99mTc-DTPA (MBq) | MO tissue | MO volume images (g)† | Hemorrhage tissue‡ |
OR1 | 7 | 3.1 | 259 | 3.7 | 13 | 28 | 3 | 5.6 | 4 |
OR2 | 7 | 3.7 | 211 | 8 | 22 | 47 | 2 | 2.3 | 4 |
OR3 | 13 | 3.3 | 226 | 8 | 25 | 37 | 1 | 0.0 | 2 |
OR4 | 14 | 3.1 | 213 | 16 | 51 | 26 | 1 | 0.0 | 2 |
OR5 | 20 | 2.6 | 218 | 3 | 12 | 37 | 1 | 0.0 | 1 |
PO1 | 7 | 2.8 | 257 | 24 | 83 | 48 | 4 | 11.6 | 3 |
PO2 | 8 | 3.0 | 255 | 17 | 62 | 47 | 4 | 4.5 | 4 |
PO3 | 13 | 3.7 | 288 | 14 | 45 | 15 | 1 | 0.0 | 1 |
PO4 | 13 | 3.3 | 221 | 16 | 52 | 41 | 2 | 1.0 | 4 |
↵* Subjects are listed as occlusion type (OR = occlusion reperfusion, PO = permanent occlusion) and day of sacrifice under Imaging day.
↵† Extent of MO in grams was also assessed from LGE in vivo 3D image.
↵‡ Sliced excised heart tissue was visually examined to confirm presence or absence of hemorrhage and scored as severe (4) to nonexistent (1).
PGL = arterial plasma glucose concentration in mmol/L; LE = 111In white blood cell labeling efficiency; MO = microvascular obstruction rated from examination of postmortem LGE images as large (4), medium (3), small (2), or nonexistent (1).