TABLE 2

Comparison of Pre-PET and Post-PET Therapeutic Plans

Pre-PET therapeutic plan
Post-PET planContinue current treatmentModify dose or scheduleSwitch to another treatmentStop treatment and switch to supportive careOverall change (%)
Scans (%)1,911 (67.3)200 (7.0)705 (24.8)23 (0.8)
All cancers40.3
 Continue current therapy1,286 (67.3)*106 (53.0)258 (36.6)11 (47.8)
 Modify dose or schedule82 (4.3)22 (11.0)*43 (6.1)2 (8.7)
 Switch to another therapy497 (26.0)64 (32.0)382 (54.2)*5 (21.7)
 Stop therapy and switch to supportive care46 (2.4)8 (4.0)22 (3.1)5 (21.7)*
Prostate cancer41.8†
 Continue current therapy790 (65.2)*76 (52.4)203 (35.6)5 (38.5)
 Modify dose or schedule46 (3.8)16 (11.0)*35 (6.1)1 (7.7)
 Switch to another therapy351 (29.0)46 (31.7)320 (56.0)*4 (30.8)
 Stop therapy and switch to supportive care24 (2.0)7 (4.8)13 (2.3)3 (23.1)*
Breast cancer39.3‡
 Continue current therapy2,534 (69.3)*16 (61.5)38 (46.9)4 (100.0)
 Modify dose or schedule17 (4.7)1 (3.8)*5 (6.2)0 (0)
 Switch to another therapy91 (24.9)9 (34.6)35 (43.2)*0 (0)
 Stop therapy and switch to supportive care4 (1.1)03 (3.7)0 (0)*
Other cancers§34.5
 Continue current therapy243 (72.5)*14 (48.3)17 (32.1)2 (33.3)
 Modify dose or schedule19 (5.7)5 (17.2)*3 (5.7)1 (16.7)
 Switch to another therapy55 (16.4)9 (31.0)27 (50.9)*1 (16.7)
 Stop therapy and switch to supportive care18 (5.4)1 (3.4)6 (11.3)2 (33.3)*

  • ↵* Agreement.

  • ↵† Difference between prostate and other cancer patients, P = 0.018.

  • ↵‡ Difference between breast cancer and other cancer patients, P = 0.20.

  • ↵§ Other cancers include lung cancer.

  • Rows are post-PET plans.