TABLE 1

t Test Statistics for K₁ Values from ¹⁵O-Water and ⁶²Cu-ETS for Normal Tissues and Metastatic Lesions

¹⁵O K₁ vs. ⁶²Cu K₁	¹⁵O K₁	⁶²Cu K₁	n	P
All samples
Baseline and therapy	0.55 ± 0.45	0.63 ± 0.42	88	0.28
Baseline	0.66 ± 0.49	0.71 ± 0.43	42	0.65
Treatment	0.45 ± 0.36	0.55 ± 0.38	46	0.25
Normal tissues
Baseline and therapy	0.46 ± 0.42	0.54 ± 0.43	53	0.33
Baseline	0.53 ± 0.42	0.58 ± 0.42	24	0.66
Treatment	0.41 ± 0.42	0.51 ± 0.45	29	0.37
All lesions
Baseline and therapy	0.69 ± 0.46	0.75 ± 0.38	35	0.56
Baseline	0.84 ± 0.53	0.87 ± 0.40	18	0.81
Treatment	0.53 ± 0.33	0.61 ± 0.32	17	0.47
Muscle
Baseline and therapy	0.05 ± 0.04	0.10 ± 0.05	18	0.00011
Baseline	0.05 ± 0.04	0.11 ± 0.02	8	0.0034
Treatment	0.05 ± 0.04	0.10 ± 0.06	10	0.072
Thyroid
Baseline and therapy	0.46 ± 0.25	0.54 ± 0.22	17	0.36
Baseline	0.61 ± 0.19	0.69 ± 0.24	8	0.79
Treatment	0.30 ± 0.17	0.41 ± 0.12	9	0.12
Myocardium
Baseline and therapy	0.88 ± 0.35	0.99 ± 0.32	18	0.31
Baseline	0.90 ± 0.32	0.97 ± 0.28	8	0.64
Treatment	0.86 ± 0.39	1.00 ± 0.37	10	0.39