TABLE 1

Binding Affinities of CCK Receptor Ligand–Targeted Radioimaging Agents in HEK 293 Cells

CompoundKd (nM) of HEK 293 CCK2R cellsKd (nM) of HEK 293 CCK2i4svR cells*
CRL-116
CRL-24631
CRL-3304
CRL-4270
  • ↵* Kd could not be determined for compounds CRL-1 and CRL-4 in HEK 293 CCK2i4svR cells because of very high levels of nonspecific binding of these compounds and significantly smaller numbers of receptors on these cells.