Biodistribution of 188Re-P2045 in AR42J Rat Pancreatic Tumor Xenograft Nude Mice After 6 Doses of 188Re-P2045 (Groups 3, 4, and 5)
| Tissue uptake of 188Re-P2045 at 3 h after injection | |||
| Tissue | Low dose (1.85 MBq) | Mid dose (5.55 MBq) | High dose (11.1 MBq) |
| Tumor | 10.2 %ID/g | 10.3 %ID/g | 10.4 %ID/g |
| Blood | 0.177 %ID/g | 0.116 %ID/g | 0.098 %ID/g |
| Kidney | 4.93 %ID/g | 3.78 %ID/g | 4.06 %ID/g |
| Gastrointestinal tract | 6.01 %ID | 4.96 %ID | 4.47 %ID |
| Tumor-to-blood | 57.6 | 88.8 | 105 |
| Tumor-to-kidney | 2.07 | 2.73 | 2.54 |
ID = 7.4 MBq of 188Re-P2045.