TABLE 1

Clinical Trial Studies Reviewed

StudyNo. of patientsActivity (MBq)Extent of scanTechniqueMean age (y)Sex
Emory initial pilot18292.3 (99.9)Skull vertex to thighs60-min dynamic brain (followed by whole-body imaging)53.8 (9.3)Male, 12; female, 6
Emory dosimetry6366.6 (51.0)Skull vertex to thighs6 sets of serial static scans for 120 min48 (15.0)Male, 3; female, 3
Emory prostate pilot15372.6 (22.9)Abdomen/pelvis65-min dynamic pelvis (followed by abdomen/pelvis)62.0 (8.8)Male, 15
Emory renal pilot6388.5 (14.1)Abdomen120-min dynamic renal-level abdomen67.3 (15.1)Male, 5; female, 1
Emory lung pilot10313.5 (76.7)Chest45-min dynamic lesion-level chest66.4 (12.8)Male, 3; female, 7
Emory recurrent prostate cancer128 scans in 115 patients358.9 (51.8)Abdomen/pelvis60-min sequential multiphase abdomen/pelvis67.3 (7.6)Male, 128
Emory primary prostate cancer11347.8 (81.4)Pelvis60-min dynamic pelvis60.8 (6.3)Male, 11
Emory breast pilot3360.0 (14.1)Chest45-min dynamic breast level60 (8.9)Female, 3
Emory parathyroid3351.5 (34.0)Neck60-min sequential multiphase neck/upper chest60.3 (6.4)Male, 1; female, 2
Emory recurrent prostate cancer outcomes13367.0 (15.5)Abdomen/pelvis30-min sequential multiphase abdomen/pelvis61.5 (9.2)Male, 13
Emory PET and MR recurrent prostate cancer6373.7 (9.4)Abdomen/pelvis30-min sequential multiphase abdomen/pelvis69 (5.1)Male, 6
Bologna recurrent prostate cancer61379 (12.1)Skull vertex to thighsSingle static scan starting at thighs67.8 (6.5)Male, 61
Kitasato phase one dosimetry6195.0 (10.3)Skull vertex to thighs11 series of whole-body PET scans during 3 sessions of 0–90, 150–170, and 220–240 min24 (3.0)Male, 6
Uppsala phase one primary prostate cancer6418 (10.0)Pelvis90 (optional 120)-min dynamic pelvis67 (5.0)Male, 6
NIH primary prostate cancer21351.5 (9.0)Pelvis/lower abdomen dynamic, whole-body static at end30-min dynamic pelvis, then 10-min dynamic lower abdomen (followed by static whole body)62 (6.5)Male, 21
Oslo University Hospital prostate and other cancers298296 (56.0)Skull vertex to thighsSingle static scan starting at thighs66.0 (6.4)Male, 297; female, 1
  • Data in parentheses are SDs.