TABLE 1

Subject Demographics

ParameterControl (n = 30)AD (n = 38)DLB (n = 30)Test
Age (y)76.3 ± 6.675.8 ± 7.576.5 ± 5.8F2,95 = 0.09, P = 0.9
Education (y)11.9 ± 2.811.5 ± 2.610.6 ± 2.3F2,95 = 1.91, P = 0.15
Sexχ2 = 2.6, P = 0.27
 Female10167
 Male202223
Duration of dementia (mo)44.0 ± 22.9 (12–132)38.1 ± 27.3 (9–120)t66 = 0.99, P = 0.3*
Mini-Mental Status Examination28.9 ± 1.1 (26–30)20.9 ± 3.7 (15–28)21.8 ± 4.2 (14–28)t66 = −1.0, P = 0.3*
Cambridge Cognitive Examination98.4 ± 4.071.3 ± 11.672.6 ± 13.1t66 = −0.43, P = 0.7*
Rey total70.3 ± 12.325.6 ± 10.033.4 ± 12.1t66 = −2.9, P = 0.005*
Cornell1.8 ± 1.84.5 ± 2.78.1 ± 3.8F2,95 = 36.2, P < 0.001
Clinician Assessment of Fluctuation scale total1.5 ± 2.56.0 ± 4.7t65 = −4.7, P < 0.001*
Neuropsychiatric Index total15.6 ± 15.419.7 ± 15.6t65 = −1.1, P = 0.3*
UPDRS2.6 ± 2.73.6 ± 3.225.5 ± 11.9F2,95 = 105, P < 0.001
  • * AD vs. DLB Student t test.

  • Motor part of UPDRS.

  • Values are mean ± SD, with range in parentheses. ANOVA Tukey post hoc tests: UPDRS = control vs. AD post hoc P = 0.8, DLB > AD and DLB > control P < 0.001. Cornell = control < AD < DLB P = 0.001. There were data only for 29 DLB for Clinician Assessment of Fluctuation scale and Neuropsychiatric Index scores.