18-Gy ALL | 24-Gy ALL | ||||||||
Survivor characteristic | Mean | SD | 95% confidence interval | P* | Mean | SD | 95% confidence interval | P* | P† |
Current age | 25.4 | 2.57 | 24.2–26.6 | 27.5 | 3.52 | 25.8–29.2 | 0.05 | ||
Age at diagnosis | 2.8 | 1.59 | 2.1–3.6 | 2.9 | 1.63 | 2.2–3.7 | 0.81 | ||
Time since diagnosis | 22.6 | 1.92 | 21.6–23.5 | 24.5 | 3.03 | 23.0–25.9 | 0.03 | ||
Neurocognitive functions | |||||||||
Global intelligence | −0.38 | 0.81 | −0.77 to 0.01 | 0.06 | −0.36 | 0.79 | −0.74 to 0.02 | 0.06 | 0.96 |
Vocabulary | −0.83 | 1.09 | −1.35 to −0.30 | 0.004 | −0.74 | 1.06 | −1.25 to −0.23 | 0.007 | 0.81 |
Word reading | −0.53 | 0.55 | −0.80 to −0.27 | <0.001 | −0.49 | 0.55 | −0.76 to −0.22 | 0.001 | 0.80 |
Calculations | −0.74 | 0.89 | −1.17 to −0.31 | 0.002 | −0.67 | 0.65 | −0.99 to −0.36 | <0.001 | 0.79 |
Visuomotor speed | −0.56 | 0.69 | −0.89 to −0.23 | 0.02 | −0.40 | 0.58 | −0.69 to −0.12 | 0.007 | 0.45 |
Oral naming speed | −0.91 | 0.77 | −1.28 to −0.54 | <0.001 | −0.98 | 0.91 | −1.42 to −0.54 | <0.001 | 0.79 |
Focused attention | −0.27 | 0.89 | −0.70 to 0.16 | 0.20 | −0.06 | 1.45 | −0.75 to 0.64 | 0.87 | 0.59 |
Sustained attention | −0.52 | 1.09 | −1.04 to 0.01 | 0.06 | −0.18 | 0.79 | −0.56 to 0.20 | 0.34 | 0.28 |
Attention span | −0.87 | 0.91 | −1.31 to −0.43 | 0.001 | −0.53 | 1.04 | −1.04 to −0.03 | 0.04 | 0.30 |
Verbal memory | −0.77 | 1.03 | −1.27 to −0.28 | 0.004 | −1.19 | 0.92 | −1.64 to −0.75 | <0.001 | 0.19 |
Working memory | −0.39 | 0.66 | −0.70 to −0.07 | 0.02 | −0.39 | 0.76 | −0.75 to −0.03 | 0.04 | 0.99 |
Cognitive flexibility | −0.88 | 1.49 | −1.60 to −0.16 | 0.02 | −1.03 | 1.33 | −1.67 to −0.39 | 0.003 | 0.75 |
Cognitive fluency | −0.12 | 0.84 | −0.53 to 0.28 | 0.53 | −0.51 | 0.88 | −0.93 to −0.07 | 0.02 | 0.18 |
↵* P values for 1-sample t tests comparing mean to value of 0.0.
↵† P values for 2 group t tests.
Values for neurocognitive functions are presented in age-adjusted z scores (mean = 0, SD = 1.0), based on national normative data; 95% confidence intervals for these scores that do not contain value of 0.0 indicate that mean for respective group falls significantly below expected value.