TABLE 1

Demographic and Treatment Characteristics and Performance on Neurocognitive Tests

	18-Gy ALL				24-Gy ALL
Survivor characteristic	Mean	SD	95% confidence interval	P^*	Mean	SD	95% confidence interval	P^*	P^†
Current age	25.4	2.57	24.2–26.6		27.5	3.52	25.8–29.2		0.05
Age at diagnosis	2.8	1.59	2.1–3.6		2.9	1.63	2.2–3.7		0.81
Time since diagnosis	22.6	1.92	21.6–23.5		24.5	3.03	23.0–25.9		0.03
Neurocognitive functions
Global intelligence	−0.38	0.81	−0.77 to 0.01	0.06	−0.36	0.79	−0.74 to 0.02	0.06	0.96
Vocabulary	−0.83	1.09	−1.35 to −0.30	0.004	−0.74	1.06	−1.25 to −0.23	0.007	0.81
Word reading	−0.53	0.55	−0.80 to −0.27	<0.001	−0.49	0.55	−0.76 to −0.22	0.001	0.80
Calculations	−0.74	0.89	−1.17 to −0.31	0.002	−0.67	0.65	−0.99 to −0.36	<0.001	0.79
Visuomotor speed	−0.56	0.69	−0.89 to −0.23	0.02	−0.40	0.58	−0.69 to −0.12	0.007	0.45
Oral naming speed	−0.91	0.77	−1.28 to −0.54	<0.001	−0.98	0.91	−1.42 to −0.54	<0.001	0.79
Focused attention	−0.27	0.89	−0.70 to 0.16	0.20	−0.06	1.45	−0.75 to 0.64	0.87	0.59
Sustained attention	−0.52	1.09	−1.04 to 0.01	0.06	−0.18	0.79	−0.56 to 0.20	0.34	0.28
Attention span	−0.87	0.91	−1.31 to −0.43	0.001	−0.53	1.04	−1.04 to −0.03	0.04	0.30
Verbal memory	−0.77	1.03	−1.27 to −0.28	0.004	−1.19	0.92	−1.64 to −0.75	<0.001	0.19
Working memory	−0.39	0.66	−0.70 to −0.07	0.02	−0.39	0.76	−0.75 to −0.03	0.04	0.99
Cognitive flexibility	−0.88	1.49	−1.60 to −0.16	0.02	−1.03	1.33	−1.67 to −0.39	0.003	0.75
Cognitive fluency	−0.12	0.84	−0.53 to 0.28	0.53	−0.51	0.88	−0.93 to −0.07	0.02	0.18

↵* P values for 1-sample t tests comparing mean to value of 0.0.
↵† P values for 2 group t tests.
Values for neurocognitive functions are presented in age-adjusted z scores (mean = 0, SD = 1.0), based on national normative data; 95% confidence intervals for these scores that do not contain value of 0.0 indicate that mean for respective group falls significantly below expected value.