Patient no. | Lesion type | 18F-FDG initial result | 18F-FDG T/BP | 18F-FMT initial result | 18F-FMT T/BP | Lesion size (cm) | Confirmation | 18F-FDG final result | 18F-FMT final result | 18F-FDG accuracy | 18F-FMT accuracy |
1 | Hypopharyngeal cancer | ++ | 4.5 | ++ | 2.6 | 5 | Histopathology | TP | TP | Correct | Correct |
Lymph node, level II R | ++ | 1.5 | ++ | 2.1 | 1.7 | Cytology | TP | TP | |||
Lymph node, level II L | ++ | 1.7 | ++ | 2.1 | 1.7 | Cytology | TP | TP | |||
Lymph node, level Vb R | ++ | 4.4 | + | 1.5 | 0.8 | CT follow-up | TP | TP | |||
Lymph node, level Vb L | ++ | 3.6 | − | − | 0.7 | CT follow-up | TP | FN | |||
2 | Hypopharyngeal cancer | ++ | 6.0 | ++ | 2.9 | 4 | Histopathology | TP | TP | Correct | Correct |
Lymph node, level III R | ++ | 5.1 | + | 1.1 | 2 | Cytology | TP | TP | |||
Lymph node, level IIa L | ++ | 4.9 | + | 1.1 | 1.7 | Cytology | TP | TP | |||
Lymph node, level III L | ++ | 5.2 | + | 1.5 | 1 | High radiologic suspicion | TP | TP | |||
Lymph node, level IV L | + | 2.3 | + | 1.2 | 0.9 | High radiologic suspicion | TP | TP | |||
3 | Oropharyngeal cancer | ++ | 6.4 | ++ | 2.3 | 3.6 | Histopathology | TP | TP | Correct | Correct |
Lymph node, level II L | ++ | 6.25 | ++ | 2.7 | 3.3 | Cytology | TP | TP | |||
4 | Cancer of tongue, L | ++ | 3.1 | + | 1.5 | 3.4 | Histopathology | TP | TP | Overstaged | Correct |
Lymph node, level IIb L | + | 1.89 | ++ | 1.7 | 1.4 | Cytology | TP | TP | |||
Lymph node, level IIb L | + | 1.9 | + | 1.3 | 1.2 | Cytology | TP | TP | |||
Tonsillary activity, R | + | 2.1 | − | − | 1.5 | Clinical follow-up | FP | TN | |||
5 | Oropharyngeal cancer R | ++ | 2.9 | + | 1.5 | 3.2 | Histopathology | TP | TP | Correct | Understaged (N) |
Lymph node, mediastinal retrocaval | ++ | 3.3 | − | − | 1.6 | High radiologic suspicion | TP | FN | |||
Lymph node, mediastinal anterior | + | 2.4 | − | − | 1.3 | High radiologic suspicion | TP | FN | |||
6 | Tonsillary cancer, R | ++ | 3 | − | − | 4.2 | Histopathology | TP | FN | Overstaged | Understaged (T) |
Lymph node, level II/III R | ++ | 6.2 | ++ | 1.8 | 1.3 | Histopathology | TP | TP | |||
Tonsillary activity, L | ++ | 3.2 | − | − | 4.1 | Clinical follow-up | FP | TN | |||
7 | Tonsillary cancer, L | ++ | 4.5 | + | 1.4 | 4.6 | Histopathology | TP | TP | Overstaged | Correct |
Tonsillary activity, R | ++ | 2.5 | − | − | 5.2 | Clinical follow-up | FP | TN | |||
Lymph node, level IIa/b L | ++ | 4.3 | + | 1.2 | 4 | Cytology | TP | TP | |||
Lymph node, level III L | ++ | 3.2 | + | 1.1 | 2.3 | Cytology | TP | TP | |||
Lymph node, level II R | ++ | 3.5 | + | 1.2 | 3.5 | Cytology | TP | TP | |||
8 | Recurrent lymph node, level III R | ++ | 5.1 | + | 1.5 | 1.4 | Histopathology | TP | TP | Overstaged | Understaged |
Lymph node, level IIa R | + | 2.8 | − | − | 3 | Histopathology | TP | FN | |||
Lymph node, mediastinal | ++ | 3.4 | − | − | 1.5 | PET/CT follow-up | FP | TN |
T/BP = tumor–to–blood pool ratio; TP = true positive; FN = false negative; FP = false positive; TN = true negative; ++ = markedly increased uptake; + = slightly increased uptake (more than background); − = no increased uptake.