Pharmacokinetic Analysis in Human NSCLC–Bearing Mice
Parameter | Unit | 188Re-BMEDA | 188Re-liposome |
Cmax | %ID/mL | 7.40 | 39.72 |
Cl | mL/h | 1.61 ± 0.18 | 0.21 ± 0.02 |
AUC(0→∞) | h·%ID/mL | 62.73 ± 7.26 | 488.97 ± 52.83 |
MRT(0→∞) | hours | 5.07 ± 3.39 | 13.04 ± 4.32 |
Cmax = larger maximal concentration; %ID = percentage injected dose; Cl = clearance; AUC(0→∞) = area under curve; MRT(0→∞) = mean residence time.