TABLE 1

Effect of Treatment on Lesion Extent

ParameterControlTreated% change
Total cholesterol, chow diet (mmol/L)20.3 ± 2.218.8 ± 2.2NS
Total cholesterol, western diet (mmol/l)85.5 ± 8.160.7 ± 6.6−29.1 (P = 0.034)
Lesion area (mm2)1.07 ± 0.110.70 ± 0.07−33.9 (P = 0.011)