PET Quantitative Categorization vs. Standard of Truth for Different Target and Reference Regions
Reference region | Composite region | SUVR Threshold | Sensitivity | Specificity | AUC |
Pons | Small | 0.62 | 91% | 88% | 0.93 |
Narrow | 0.58 | 91% | 84% | 0.93 | |
Large | 0.56 | 91% | 84% | 0.92 | |
Cerebellar gray matter | Small | 1.67 | 86% | 88% | 0.90 |
Narrow | 1.57 | 86% | 88% | 0.89 | |
Large | 1.63 | 86% | 88% | 0.87 | |
Whole cerebellum | Small | 1.30 | 91% | 84% | 0.92 |
Narrow | 1.27 | 88% | 84% | 0.92 | |
Large | 1.23 | 88% | 84% | 0.90 |