TABLE 2

Results of Multivariate Cox Regression Analyses

	Covariate added to Cox regression
	Age		Glioma grade		Time since radiotherapy		Tumor SUV
AMT PET predictors	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Thalamic SUV	2.2 (1.3–3.8)	0.005^*	1.6 (0.9–2.9)	0.1	1.9 (1.1–3.3)	0.015^*	1.7 (0.9–3.2)	0.1
Frontal SUV	2.2 (1.04–4.6)	0.04^*	1.5 (0.7–3.3)	0.29	1.9 (0.95–3.9)	0.07	1.4 (0.6–3.4)	0.37
Thalamocortical SUV ratio	1776 (25–122,730)	0.001^*	597 (6.3–56,621)	0.005^*	329 (4–25,649)	0.009^*	506 (4.9–51,784)	0.008^*

↵* P value is significant.
HR = hazard ratio; CI = confidence interval.
Clinical variables and mean tumoral SUV were entered as covariates for each of the contralateral AMT predictors found significant in univariate analysis. Hazard ratios are given for AMT PET predictors after addition of each covariate to model. Thalamocortical AMT SUV ratio remained highly prognostic for survival with each of the covariates.