TABLE 1

SLN Accumulation

Number of SLNsLocation of SLNsTime (h)Tilmanocept injected (nmol)Percentage injected dose*IRDye800CW (nmol)Extraction (%)*Fluorescence intensity (kcts s−1 μW−1)
8Popliteal1.01.70.95 ± 0.780.024 ± 0.02099.4 ± 4.06.22 ± 2.45
8Popliteal36.01.70.56 ± 0.390.014 ± 0.01098.5 ± 0.98.62 ± 3.72
8Popliteal1.08.41.64 ± 0.770.21 ± 0.1095.1 ± 5.219.1 ± 9.23
8Popliteal36.08.41.21 ± 0.330.15 ± 0.0494.2 ± 5.911.6 ± 4.24
  • * Measured by γ well counter (100–200 keV).

  • Measured by Optix MX2.

  • P < 0.05 for comparison with data from same time but different amount of injected tilmanocept.

  • Data are mean ± SD.