TABLE 1

Statistics on Conjugation of Antibody Constructs

AntibodyChelateAbbreviated nameActive ester used (eq)Substitution amount (DOTA/Ab)Scale (mg)
HuM1953-arm DOTA3A-HuM15, 30, 604.5, 9.9*, 18.310
4-arm DOTA4A-HuM30, 4010.3*, 13.15
Rituximab3-arm DOTA3A-Rit609.5*5
4-arm DOTA4A-Rit309.8*5
  • * These constructs were used in further studies as described in text.