AEs Noted from Radiopharmaceuticals
Event | Radiopharmaceutical |
Cutaneous (rash, flush) | 99mTc-DMSA†, 18F-FDG, 111In-WBC*, 111In-WBC/99mTc-SC/99mTc-MDP, 99mTc-MAG3/furosemide, 99mTc-MDP, 99mTc-MDP/99mTc-SC, 123I-MIBG (2 patients)†, cold pyp†, 99mTc-sestamibi, 131I-tositumomab |
Nausea | 123I-MIBG (2 patients)†, 99mTc-DMSA† |
Cardiovascular (anaphylactoid, hypotension, cardiac arrest) | 99mTc-MDP (2 patients)*, 99mTc-SC, 18F-FDG*, 99mTc-MAG3/furosemide |
Neurologic (pain, hypesthesia, paresthesia) | Cold pyp†, 99mTc-sestamibi*, 99mTc-tetrofosmin (2 patients)* |
↵* Judged as unlikely by study criteria, totaling 5 AEs; if 2 patients are noted as having had AEs, only one was deemed unlikely in this study.
↵† Three patients (1 each from 99mTc-DMSA, 123I-MIBG, cold pyp) had 2 symptoms or signs from radiopharmaceuticals, but these were counted as 1 AE from 1 radiopharmaceutical that caused 2 symptoms.
DMSA = dimercaptosuccinic acid; WBC = white blood cells; SC = sulfur colloid; MDP = methylene diphosphonate; MAG3 = mercaptoacetyltriglycine; MIBG = metaiodobenzylguanidine; pyp = pyrophosphate.