TABLE 2

AEs Noted from Radiopharmaceuticals

EventRadiopharmaceutical
Cutaneous (rash, flush)99mTc-DMSA, 18F-FDG, 111In-WBC*, 111In-WBC/99mTc-SC/99mTc-MDP, 99mTc-MAG3/furosemide, 99mTc-MDP, 99mTc-MDP/99mTc-SC, 123I-MIBG (2 patients), cold pyp, 99mTc-sestamibi, 131I-tositumomab
Nausea123I-MIBG (2 patients), 99mTc-DMSA
Cardiovascular (anaphylactoid, hypotension, cardiac arrest)99mTc-MDP (2 patients)*, 99mTc-SC, 18F-FDG*, 99mTc-MAG3/furosemide
Neurologic (pain, hypesthesia, paresthesia)Cold pyp, 99mTc-sestamibi*, 99mTc-tetrofosmin (2 patients)*
  • * Judged as unlikely by study criteria, totaling 5 AEs; if 2 patients are noted as having had AEs, only one was deemed unlikely in this study.

  • Three patients (1 each from 99mTc-DMSA, 123I-MIBG, cold pyp) had 2 symptoms or signs from radiopharmaceuticals, but these were counted as 1 AE from 1 radiopharmaceutical that caused 2 symptoms.

  • DMSA = dimercaptosuccinic acid; WBC = white blood cells; SC = sulfur colloid; MDP = methylene diphosphonate; MAG3 = mercaptoacetyltriglycine; MIBG = metaiodobenzylguanidine; pyp = pyrophosphate.