Tracking Accuracy of SPECT/CT for 125I-IL-13PE Distribution After Bolus Injection or CED into Glioma-Bearing Mouse Brain
SPECT | |||||
Animal no. | Injection method | Time after injection | Autoradiography, Vd (mm3) | Vd (mm3) | Percentage difference with autoradiography |
1 | Bolus | Day 1 | 9.78 | 4.10 | −41.9 |
2 | Bolus | Day 7 | 1.51 | Not available | Not available |
3 | Bolus | Day 7 | 0.72 | Not available | Not available |
4 | Bolus | Day 7 | 1.04 | Not available | Not available |
5 | CED | Day 1 | 36.6 | 20.3 | −55.4 |
6 | CED | Day 7 | 15.7 | 8.19 | −52.2 |
7 | CED | Day 7 | 19.1 | 7.68 | −40.3 |
8 | CED | Day 7 | 20.3 | 12.5 | −61.7 |