Demographic Characteristics and Clinical Diagnosis (per Reference Standard) by Study
| Study | ||||||
| Characteristic and diagnosis | A (n = 220) | B (n = 326) | C (n = 102) | D (n = 78) | E (n = 92) | Total (n = 818) |
| Age (y) | NA | |||||
| Mean ± SD | 62.7 ± 8.87 | 73.9 ± 7.17 | 60.4 ± 10.91 | 64.2 ± 11.99 | 67.9 ± 12.21 | |
| Minimum | 40 | 54 | 33 | 25 | 19 | |
| Maximum | 80 | 90 | 79 | 84 | 87 | |
| Median | 63.5 | 75.0 | 61.0 | 67.0 | 68.0 | |
| Sex | ||||||
| Male | 136 (62) | 187 (57) | 57 (56) | 41 (53) | 50 (54) | 471 (58) |
| Female | 84 (38) | 139 (43) | 45 (44) | 37 (47) | 42 (46) | 347 (42) |
| Race | ||||||
| Caucasian | 216 (98) | 326 (100) | 102 (100) | 77 (99) | 91 (99) | 812 (99) |
| Black | 3 (1) | 0 (0) | 0 (0) | 0 (0) | 1 (1) | 4 (<1) |
| Asian | 1 (<1) | 0 (0) | 0 (0) | 1 (1) | 0 (0) | 2 (<1) |
| Other | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| PS (SDD) | 158 (72) | 0 (0) | 71 (70) | 48 (62) | 50 (54) | 327 (40) |
| Possible PS | 158 (72) | 0 (0) | 5 (5) | 48 (62) | 0 | 211 (26) |
| Probable PS | 0 (0) | 0 (0) | 66 (65) | 0 (0) | 50 (54) | 116 (14) |
| DLB (SDD) | 0 (0) | 116 (36) | 0 (0) | 0 (0) | 0 (0) | 116 (14) |
| Possible DLB | 0 (0) | 27 (8) | 0 (0) | 0 (0) | 0 (0) | 27 (3) |
| Probable DLB | 0 (0) | 89 (27) | 0 (0) | 0 (0) | 0 (0) | 89 (11) |
| Non-PS/Non-DLB (no SDD) | 62 (28) | 210 (64) | 31 (30) | 30 (38) | 42 (46) | 375 (46) |
| ET | 27 (12) | 0 (0) | 14 (14) | 23 (29) | 20 (22) | 84 (10) |
| AD | 0 (0) | 125 (38) | 0 (0) | 0 (0) | 0 (0) | 125 (15) |
| Other* | 35 (16) | 85* (26) | 17 (17) | 7 (9) | 22 (24) | 166 (20) |
| SDD present† | 158 (72) | 116 (36) | 71 (70) | 48 (62) | 50 (54) | 443 (54) |
| SDD absent | 62 (28) | 210 (64) | 31 (30) | 30 (38) | 42 (46) | 375 (46) |
↵* Other includes other (n = 1), no diagnosis (n = 22), and not assessed at 12 mo (n = 62).
↵† Includes possible and probable PS and possible and probable DLB diagnoses.
NA = not applicable; ET = essential tremor; AD = Alzheimer disease.
Intent-to-diagnose populations used for studies A (4), B (5,6), C (1), and D (3,8). Per-protocol population used for study E (2,7). Data in parentheses are percentages.