TABLE 1

Characteristics of Patients with Neuroendocrine Tumors and Chronic Kidney Insufficiency

CharacteristicPatient 1Patient 2Patient 3Patient 4
Age (y)77744474
SexFMFF
DiagnosisNeuroendocrine carcinoma (bladder)Neuroendocrine tumor (lung)Neuroendocrine tumor (ileum)Neuroendocrine tumor (ileum)
Tumor gradeG3G1G2G2
First diagnosed5 mo ago3 y ago5 y ago11 mo ago
Pretreatment evaluation
 ECOG performance status2010
 Remission status*PDPDPDPD
 Chronic kidney diseaseGrade 3Grade 3Grade 2Grade 3
Three-mo follow-up
 ECOG performance status2000
 Remission status*Mixed responsePRSDPR
 Chronic kidney diseaseGrade 3Grade 3Grade 2Grade 3
Adverse events
 Anemia (reversible)Grade 2Grade 1Grade 2Grade 2
 Leukopenia (reversible)Grade 2Grade 1Grade 2Grade 0
 Thrombocytopenia (reversible)Grade 0Grade 3Grade 0Grade 0
Maximum follow-up (mo)15121312
 Remission statusPDPRSDPR
  • * Response was assessed with CT according to the Response Evaluation Criteria in Solid Tumors, version 1.1.

  • Chronic kidney disease was graded according to the guidelines of the National Kidney Foundation.

  • Adverse events were graded according to the Common Terminology Criteria for Adverse Events, version 4.0, of the National Cancer Institute.

  • ECOG = Eastern Cooperative Oncology Group; PD = progressive disease; PR = partial response; SD = stable disease.