Univariate Analysis of Relationship Between Tumor Shrinkage at 2 Months and Covariates Evaluated at Tumor Level
| Correlation with tumor volume shrinkage | ||||
| Parameter | Median | n | P | r* |
| Baseline tumor volume (mL) | 20 (1–716) | 130 | 0.078 | −0.166 |
| Initial shrinkage (during tracer imaging) (%) | 10 (–48 to 47) | 130 | 0.163 | 0.132 |
| Tracer-predicted mean tumor-absorbed dose (cGy) | 248 (80–768) | 130 | 0.002 | 0.290 |
| Therapy-delivered mean tumor-absorbed dose (cGy) | 275 (94–711) | 124 | 0.021 | 0.222 |
| Therapy-delivered minimum tumor dose (cGy) | 130 (2–382) | 124 | 0.078 | 0.171 |
| Therapy-delivered tumor D99 (cGy) | 156 (29–408) | 124 | 0.034 | 0.204 |
| Therapy-delivered tumor D80 (cGy) | 216 (58–481) | 124 | 0.021 | 0.222 |
| Therapy-delivered equivalent biologic effect | 0.87 (0.004−6.57) | 124 | <0.0001 | 0.490 |
↵* Spearman rank correlation was used.
D99 and D80 = absorbed dose received or exceeded by 99% and 80%, respectively.
Data in parentheses are ranges.