TABLE 4

Radiation Dose Estimates of 18F-MCL-524 for Different Organs

Estimated dose (mSv/MBq)
OrganM4M5Mean
Gallbladder wall0.2330.3000.267
ULI wall0.1660.2160.191
Small intestine0.1460.1890.168
Thyroid0.0330.1400.086
Urinary bladder wall0.0720.0930.082
LLI wall0.0570.0710.064
Kidneys0.0340.0550.044
Ovaries0.0310.0360.034
Uterus0.0270.0310.029
Liver0.0200.0250.022
Lungs0.0250.0170.021
Stomach wall0.0140.0140.014
Pancreas0.0140.0140.014
Spleen0.0120.0110.011
Red marrow0.0110.0110.011
Adrenals0.0110.0100.011
Heart wall0.0100.0100.010
Osteogenic cells0.0110.0080.009
Muscle0.0090.0090.009
Testes0.0070.0060.007
Brain0.0060.0060.006
Thymus0.0070.0040.005
Skin0.0060.0040.005
Breasts0.0060.0040.005
Total body0.0120.0120.012
Effective dose0.0310.0400.035
  • ULI = upper large intestine; LLI = lower large intestine.