Organ | 1 h | 1 h blocked | 1 h/Gelofusine | 4 h | 24 h |
Blood | 0.4 ± 0.1 | 0.6 ± 0.02 | 0.5 ± 0.1 | 0.04 ± 0.01 | 0.01 ± 0.00 |
Heart | 0.2 ± 0.03 | 0.3 ± 0.06 | 0.3 ± 0.13 | 0.1 ± 0.02 | 0.1 ± 0.03 |
Liver | 2.0 ± 0.5 | 2.7 ± 0.7 | 2.6 ± 0.6 | 1.6 ± 0.1 | 2.2 ± 0.3 |
Spleen | 3.6 ± 0.9 | 4.5 ± 0.6 | 4.6 ± 0.5 | 2.5 ± 0.4 | Not determined |
Lung | 7.8 ± 0.9 | 13.1 ± 3.0 | 7.2 ± 1.4 | 2.0 ± 0.7 | 0.9 ± 0.3 |
Kidney | 217 ± 39 | 209 ± 17 | 125 ± 5 | 205 ± 34 | 173 ± 28 |
Stomach | 0.6 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.2 | 0.3 ± 0.06 | 0.3 ± 0.04 |
Intestine | 0.5 ± 0.2 | 1.0 ± 0.07 | 1.4 ± 0.4 | 0.5 ± 0.6 | 0.2 ± 0.03 |
Adrenal | 1.5 ± 0.8 | 0.6 ± 0.5 | 1.4 ± 0.4 | 1.9 ± 1.5 | 0.7 ± 0.2 |
Pancreas | 0.2 ± 0.06 | 0.2 ± 0.04 | 0.2 ± 0.06 | 0.1 ± 0.01 | 0.06 ± 0.03 |
Muscle | 0.2 ± 0.04 | 0.1 ± 0.05 | 0.3 ± 0.16 | 0.1 ± 0.06 | 0.06 ± 0.03 |
Bone | 0.4 ± 0.08 | 0.3 ± 0.04 | 0.8 ± 0.45 | 0.3 ± 0.06 | 0.3 ± 0.3 |
INR1G9 tumor | 10.4 ± 2.2 | 2.0 ± 0.2 | 9.2 ± 0.7 | 6.6 ± 1.3 | 3.6 ± 0.7 |
Tumor/blood | 28 ± 9 | 21 ± 6 | 156 ± 22 | 320 ± 51 | |
Tumor/lung | 1.2 ± 0.03 | 1.3 ± 0.2 | 2.4 ± 0.9 | 3.1 ± 1.2 | |
Tumor/kidney | 0.05 ± 0.01 | 0.07 ± 0.01 | 0.03 ± 0.00 | 0.02 ± 0.01 | |
Tumor/muscle | 64 ± 14 | 32 ± 17 | 54 ± 19.31 | 68 ± 32 |
Data are presented as mean ± SD (n = 4) %IA/g of tissue; blocking studies were performed in presence of 20 nmol of GIP(1–30).