VT and BPND Estimates for MA1 Fits of Regional Time–Activity Curves
| VT | BPND | |||||
| Region | Average* | ΔVT† | ICC‡ | Average* | ΔBPND§ | ICC‡ |
| Cerebellum | 4.7 ± 0.7 (14%) | 2% ± 18% (12%) | 0.28 (−0.44; 0.79) | |||
| Caudate | 13.2 ± 1.8 (14%) | 0% ± 15% (11%) | 0.81 (0.35; 0.96) | 1.8 ± 0.2 (9%) | −2% ± 10% (9%) | 0.92 (0.69; 0.98) |
| Putamen | 15.8 ± 1.9 (12%) | −1% ± 13% (9%) | 0.72 (0.16; 0.94) | 2.4 ± 0.2 (8%) | −4% ± 11% (9%) | 0.57 (−0.11; 0.89) |
| Pallidum | 20.1 ± 3.2 (16%) | −2% ± 14% (9%) | 0.88 (0.54; 0.97) | 3.3 ± 0.6 (17%) | −6% ± 11% (6%) | 0.87 (0.51; 0.97) |
| Ventral striatum | 22.2 ± 4.9 (22%) | 0% ± 21% (15%) | 0.64 (0.01; 0.92) | 3.7 ± 0.6 (15%) | −2% ± 12% (10%) | 0.82 (0.38; 0.96) |
| Amygdala | 5.9 ± 0.8 (14%) | −1% ± 15% (10%) | 0.51 (−0.19; 0.88) | 0.26 ± 0.07 (26%) | −13% ± 29% (25%) | 0.29 (−0.42; 0.80) |
| SN | 13.4 ± 2.6 (19%) | −9% ± 25% (21%) | 0.85 (0.45; 0.97) | 1.8 ± 0.4 (19%) | −16% ± 17% (19%) | 0.92 (0.68; 0.98) |
| Thalamus | 6.4 ± 1.2 (18%) | 2% ± 17% (13%) | 0.55 (−0.13; 0.89) | 0.36 ± 0.10 (28%) | 2% ± 19% (14%) | 0.73 (0.17; 0.94) |
| Hypothalamus | 12.4 ± 2.7 (22%) | −3% ± 14% (11%) | 0.80 (0.32; 0.95) | 1.7 ± 0.8 (48%) | −7% ± 27% (21%) | 0.55 (−0.14; 0.89) |
↵* n = 5 HCs; data are presented as mean ± SD (relative SD) across subjects.
↵† n = 8 subjects; data are presented as m(∆VT) ± σ(∆VT) (m(|∆VT|)).
↵‡ n = 8 subjects; ICC is presented as estimate, with lower and upper bounds of 95% confidence interval in parentheses.
↵§ n = 8 subjects; data are presented as m(∆BPND) ± σ(∆BPND) (m(|∆BPND|)).