TABLE 4

Previous Meta-Analyses of HNC

StudyYearCountryNo. of studiesNo. of patientsClassificationEffect size
Yongkui et al. (29)2013China14742Pretreatment, staging, detection of regional nodal metastasisSensitivity/specificity
Xu et al. (31)2012China81,147Pretreatment, staging, detection of distant malignanciesSensitivity/specificity
Xu et al. (32)2011China121,276Pretreatment, staging, detection of distant metastases and second primary cancersSensitivity/specificity
Kyzas et al. (30)2008Greece321,236Pretreatment, staging, detection of cervical node metastasesSensitivity/specificity
Yi et al. (33)2013China172,912Pretreatment, staging, detection of bone metastasisSensitivity/specificity
Xu et al. (34)2011China151,445Pretreatment, staging, detection of distant metastasisSensitivity/specificity
Isles et al. (36)2008United Kingdom27917Posttreatment, follow-up, detection of residual or recurrent disease after chemoradiotherapySensitivity/specificity
Gupta et al. (35)2011India512,335Posttreatment, follow-up, detection of residual or recurrent disease or metastasisSensitivity/specificity
Zhang et al. (37)2010China8495Prognosis, DFS/OSRisk ratio
Xie et al. (38)2011China261,415Prognosis, DFS/OS/LRCOdds ratio
  • DFS = disease-free survival; LRC = locoregional control.