TABLE 1

Biodistribution Results of 64CuCl2 in B16F10 and A375M Tumor-Bearing Mice (n = 4)

OrganB16F10A375M
Blood1.51 ± 0.191.94 ± 0.56
Heart5.16 ± 0.738.85 ± 0.65
Lungs6.64 ± 0.4810.17 ± 1.58
Liver14.06 ± 2.3313.37 ± 1.32
Spleen3.46 ± 0.424.59 ± 0.10
Pancreas2.74 ± 0.363.48 ± 0.61
Stomach3.92 ± 0.826.47 ± 0.86
Brain0.88 ± 0.091.00 ± 0.07
Intestine4.35 ± 0.996.82 ± 0.40
Kidneys11.86 ± 0.5610.34 ± 0.53
Skin1.18 ± 0.511.95 ± 0.36
Muscle1.03 ± 0.181.13 ± 0.36
Bone1.66 ± 0.241.82 ± 0.24
Tumor4.14 ± 0.243.59 ± 0.36
Uptake ratio
 Tumor to blood2.79 ± 0.421.94 ± 0.44
 Tumor to lung0.63 ± 0.070.36 ± 0.04
 Tumor to liver0.30 ± 0.040.26 ± 0.04
 Tumor to muscle4.11 ± 0.073.46 ± 1.25
  • Data are presented as percentage injected dose per gram (%ID/g) ± SD.