Biodistribution of 64Cu in Tumor-Bearing Mice at 24 Hours After Injection of 64CuCl2
| Tissue | Tissue 64Cu radioactivity from mice with PC-3 prostate cancer xenografts (%ID/g) | Tissue 64Cu radioactivity from mice with DU-145 prostate cancer xenografts (%ID/g) |
| Liver | 22.7 ± 14.2 | 20.1 ± 8.8 |
| Spleen | 3.9 ± 1.4 | 5.0 ± 5.7 |
| Kidney | 12.4 ± 6.1 | 5.3 ± 3.0 |
| Heart | 7.2 ± 4.9 | 2.7 ± 0.9 |
| Muscle | 1.0 ± 0.6 | 0.4 ± 0.3 |
| Brain | 0.9 ± 0.7 | 0.3 ± 0.1 |
| Blood | 2.0 ± 1.0 | 1.5 ± 0.5 |
| Testis | 1.3 ± 0.4 | 0.9 ± 0.5 |
| Tumors without knockdown of hCtr1 | 6.6 ± 1.1 (Lenti-SCR-shRNA-PC-3) | 5.7 ± 5.3 (Lenti-SCR-shRNA-DU-145) |
| Tumors with knockdown of hCtr1 | 3.6 ± 0.7 (Lenti-hCtr1-shRNA-PC-3) | 2.8 ± 2.0 (Lenti-hCtr1-shRNA-DU-145) |