TABLE 1

Summarized High-Performance Liquid Chromatography/Mass Spectrometry Concentrations of Iobenguane and Related Chemical Species for HSA ¹²³I-Iobenguane (n = 6)

Parameter	¹²³I-MIBG	¹²⁷I-MIBG	All MIBG^*	mHBG^†	BG^‡	All API species
Content (ng/mL)	4.7 ± 3.1^§	9.6 ± 9.1^§	14.3	13.2 ± 3.0^§	362.8 ± 55.1^§	390.3
Content (nmol/mL)	0.0173	0.0348	0.052	0.0795	2.4187	2.55
Specific activity dose
GBq/μmol	5,353.3	2,659.4	1,775.8	1,163.2	38.2	36.26
mCi/μmol	144,684	71,876	47,994	31,439	1,033	980.4^║

↵* Molecular weight = 272 or 276.
↵† Molecular weight = 166.
↵‡ Molecular weight = 150.
↵§ Sample SD = σ_xn-1 and N equals degrees of freedom.
↵║ Apparent specific activity.
mHBG = meta-hydroxybenzylguanidine; BG = benzylguanidine; API = active pharmaceutical ingredient.