Change in Management Associated with NaF PET Categorized as Treatment Versus Nontreatment and Stratified by Indication
| Treatment plan | ||||
| Before PET | After PET | Initial staging (n = 1,024) | Suspected FOM (n = 1,997) | Suspected POM (n = 510) |
| Nontreatment | Nontreatment | 183 (17.9) | 777 (38.9) | 122 (23.9) |
| Treatment | Treatment | 363 (35.4) | 339 (17.0) | 123 (24.1) |
| Nontreatment | Treatment | 424 (41.4) | 703 (35.2) | 239 (46.9) |
| Treatment | Nontreatment | 54 (5.3) | 178 (8.9) | 26 (5.1) |
| Rate of change in management | 46.7% (95% CI, 43.6–49.7) | 44.1 (95% CI, 41.9–46.3) | 52.0 (95% CI, 47.6–56.3) | |
| Imaging-adjusted rate* | 12.2% (95% CI, 10.2–14.2) | 15.8 (95% CI, 14.2–17.4) | 12.4 (95% CI, 9.5–15.2) | |
↵* Adjusted to assume no effect of NaF PET for cases with pre-PET plan of imaging.
Difference between pre- and post-PET plans (rows) is compared with indication for scan (columns). Data in parentheses are percentages.
CI = confidence interval.