TABLE 1

Clinical and Imaging Results

						Global tumor		¹⁸F-FET PET–guided approach		ADC MR imaging–guided approach
Patient no.	Age (y)	Sex	Tumor stage	Histology	Tumor volume (mL)	¹⁸F-FET uptake	ADC	Focal maximum ¹⁸F-FET uptake	Corresponding ADC	ADC in most diffusion restricted area	Corresponding ¹⁸F-FET uptake
1	44	F	Rec	OA	16.98	1.90	1.38	3.60	1.04	0.94	1.84
2	33	M	Rec	OD	13.05	1.65	1.23	2.58	1.47	1.07	2.12
3	38	M	Pro	OD	29.31	1.10	1.28	2.22	1.32	0.93	0.99
4	38	F	Rec	OA	4.39	1.22	1.88	1.85	2.14	1.57	1.54
5	57	F	Pro	OA	5.87	1.09	1.42	1.52	1.37	1.16	1.07
6	42	M	Pro	OA	20.61	0.85	1.44	1.17	1.08	0.91	0.69
7	41	M	New	OA	27.48	0.83	1.20	1.11	1.19	0.94	0.76
8	60	F	New	FA	11.35	2.31	1.17	3.80	1.24	1.13	3.52
9	48	F	New	FA	21.30	1.00	1.18	1.74	1.13	1.02	1.01
10	33	M	New	FA	31.09	1.25	1.56	1.68	1.30	1.33	1.62
11	42	F	New	FA	21.34	1.01	1.36	1.34	1.55	0.97	0.97
12	53	M	New	FA	4.43	1.02	0.94	1.22	0.90	0.82	1.08
13	49	F	New	FA	54.38	0.88	1.72	1.20	1.66	1.00	0.71
14	64	M	New	FA	27.88	0.97	1.20	1.15	1.12	0.90	0.93
15	47	M	New	FA	73.54	0.90	1.60	1.15	1.85	0.93	1.02
16	74	F	Rec	FA	23.93	0.94	1.65	1.11	1.92	1.16	0.96
17	41	M	New	FA	8.62	0.78	1.68	0.98	1.67	1.54	0.74
18	62	M	New	FA	42.03	0.89	0.91	0.95	0.97	0.82	0.81

Data are grouped by histology and then ranked by maximum focal metabolic activity (¹⁸F-FET uptake). Tumor volumes are derived from MR images. PET values are presented as tumor-to-cerebellum uptake ratios. ADC values are presented in units of 10⁻³ mm²/s.
OA = oligoastrocytoma; OD = oligodendroglioma; FA = fibrillary astrocytoma; Rec = recurrent; Pro = progressive; New = newly diagnosed.