NaF PET Findings, Post-PET Extent of Disease, and Treatments Planned
| Characteristic | Initial staging (n = 1,024) | Suspected FOM (n = 1,997) | Suspected POM (n = 510) |
| NaF PET findings (%) | |||
| Benign | 71.0 | 52.0 | 16.1 |
| Equivocal | 8.5 | 8.0 | 1.6 |
| Probable | 6.3 | 11.0 | 5.9 |
| Definite | 13.9 | 29.0 | 76.5 |
| Unifocal | 2.0 | 3.4 | 3.3 |
| Multifocal | 8.7 | 19.0 | 47.8 |
| Diffuse | 3.2 | 6.7 | 25.3 |
| Avoid diagnostic tests (%) | 69.3 | 75.2 | 79.6 |
| Avoid invasive procedures (%) | 51.3 | 58.7 | 55.9 |
| Treatment* | 76.9 | 52.2 | 71.0 |
| Local therapies | 58.6 | 10.5 | 2.4 |
| Surgery | 18.5 | 1.8† | 0.4§ |
| Radiotherapy | 52.2 | 10.5 | 3.7 |
| Directed at bone | 10.8 | 19.3 | 39.2 |
| Radiotherapy | 5.3 | 7.8 | 15.3 |
| Radiopharmaceutical therapy | 0.1‡ | 1.1 | 2.4 |
| Bisphosphonates | 6.7 | 11.5 | 27.8 |
| Systemic therapies | 38.0 | 41.6 | 61.4 |
| Hormonal | 35.4 | 32.3 | 40.8 |
| Chemotherapy | 7.9‡ | 13.5 | 29.0 |
| Immunotherapy | 2.4‡ | 6.2§ | 7.6§ |