TABLE 2

Biodistribution of ¹²⁵I-MORAb-004 in Naïve Mice at Various Times After Injection^*

Organ	4 h (n = 6)	24 h (n = 5)	48 h (n = 6)	72 h (n = 4)	6 d (n = 4)
Blood	22.39 ± 1.47	11.64 ± 0.95	10.53 ± 1.32	8.93 ± 1.30	5.64 ± 0.50
Heart	4.40 ± 0.38	2.26 ± 0.32	2.40 ± 0.52	1.94 ± 0.30	1.06 ± 0.10
Lungs	8.85 ± 1.06	4.88 ± 0.47	4.58 ± 0.66	3.76 ± 0.80	2.20 ± 0.15
Kidney	4.61 ± 0.69	2.32 ± 0.57	2.28 ± 0.62	2.06 ± 0.69	1.14 ± 0.27
Spleen	6.17 ± 1.20	3.20 ± 0.84	2.88 ± 0.46	2.71 ± 0.42	1.40 ± 0.29
Liver	5.56 ± 0.71	2.41 ± 0.57	2.21 ± 0.31	2.00 ± 0.22	1.03 ± 0.22
Muscle	0.69 ± 0.31	1.36 ± 0.44	1.28 ± 0.69	1.11 ± 0.18	0.55 ± 0.18
Brain	0.77 ± 0.11	0.37 ± 0.08	0.40 ± 0.09	0.29 ± 0.09	0.18 ± 0.01
Uterus	7.55 ± 1.54	3.86 ± 1.16	4.06 ± 1.49	4.57 ± 0.31	2.30 ± 0.47
Ovaries	6.98 ± 0.75	5.36 ± 2.18	5.75 ± 1.81	4.42 ± 1.31	2.30 ± 0.18
Thyroid^†	0.56 ± 0.29	0.87 ± 0.55	0.90 ± 0.39	0.60 ± 0.37	1.16 ± 0.99

↵* Data are expressed as %ID/g ± SD; mice injected with 0.185 MBq (5 μCi); 2.5 μg of IgG.
↵† Data are expressed as %ID/org ± SD.