TABLE 1

Healthy Participant Population Demographics, MR Imaging Findings, and 18F-GE-179 Injection Data

Patient identification no.Age (y)SexWeight (kg)HandednessSmokerMR imagingInjected dose (MBq)Specific activity at time of injection (GBq/μmol)Purity (%)Coinjected mass (μg)
126M80LNoNormal187.0450.1980.16
231M67RNoNormal173.273.1970.91
355M83RYesWM foci186.01428.0970.05
437F58RNoTiny WM foci180.4769.5960.09
561M65RNoNormal183.7881.5950.08
662F53RNoWM foci185.3229.5960.31
7*25F81RNoNormal192.4263.8960.28
826M91LNoNormal189.2726.6960.10
957M84RNoRF WM foci186.9311.9960.23
Median/total376 M807 right1 smokerNA186.0450.1960.16
CV (%)172.870.01102
IQR26–5765–83183.7–187.0263.8–769.596–970.09–0.28
Minimum2553173.273.1950.05
Maximum6291192.41428.0980.91
  • * Participant 7 was a regular user of ibuprofen. Analysis by ANOVA failed to demonstrate any significant influence of this variable on AUCmetabs or AUCIF.

  • WM = white matter; RF = right frontal; NA = nonapplicable.