TABLE 4

Pulmonary Distribution of 68Ga-NOTA-UBI29-41 in Rabbits: Quantification of Lung Tissue

PET/CT image acquisition (min) after injection†
T/NT* ratio (lung to muscle)5306090120
Healthy (NZR-1)ND2.5 ± 0.632.5 ± 0.53ND3.0 ± 0.55
Infection/inflammation (NZR-2)1.9 ± 0.532.5 ± 0.792.2 ± 0.492.7 ± 1.01ND
Asthma (NZR-3)2.1‡2.4 ± 0.452.5 ± 0.44NDND

  • ↵* Nontargeted tissue (frontal leg triceps).

  • ↵† Values represent mean ± SD of > 3 animals/group.

  • ↵‡ Lung-to-muscle ratio calculated from single animal.

  • ND = value not determined.