TABLE 1

Demographic and Clinical Characteristics of Patients

Patient no.Months from diagnosisPrimarySurgeryTumor burdenKi-67Earlier treatmentOngoing treatmentBody mass indexHormones
1 (F, 67 y)8PancreasIleocecal resection (ileus)Pancreas, liver3%STZ + 5-FU, lanreotide,* SD18.9 (50 kg)CgA 62, Glu 214, Ins 171
2 (M, 53 y)72Lung, pancreasPancreasPancreas, lung, liver11%22.2 (70 kg)
3 (F, 73 y)36PancreasPancreas, liver31%STZ + 5-FUOctreotide acetate, long-acting*26.1 (71 kg)CgA 9.1
4 (M, 67 y)72Small intestineSmall-intestine resectionLiver, LN, paraaortal<1%IFN-α + octreotide acetate, long-acting,* SD23.6 (79 kg)CgA 20, U-5HIAA 31
5 (M, 58 y)5Small intestinePrimary liver, LN, mesentery, paraaortal2%–3%24.8 (75 kg)CgA 1,640, U-5HIAA 2,457
6 (F, 63 y)3Small intestinePrimary liver, LN, abd, bone<1%22.3 (58.6 kg)CgA 406, U-5HIAA 285
7 (M, 50 y)2Small intestineSmall intestine, LN, mesentery, omentumLiver, LN, abd, mediastinum12%–18%Octreotide acetate, long-acting*23.3 (85.1 kg)CgA 8.2, U-5-HIAA 100
8 (M, 65 y)48PancreasPancreas, liver25%–30%Carbo-VP 16, TMZ/CapTMZ + bevacizumab, SD24.6 (71 kg)CgA 20, PP 280
9 (F, 75 y)22LungLeft pulmectomyLiver33 (80.5 kg)CgA 7.2
10 (M, 44 y)5Small intestineSmall-intestine resectionMesentary, peritoneum10%36 (120.5 kg)CgA 6.0
  • * Stopped 4 wk before PET examination.

  • STZ = streptozotocin; 5-FU = 5-fluorouracil; SD = stable disease; CgA = chromogranin A (nmol/L); Glu = glucagon (ng/L); Ins = insulin (mE/L); LN = lymph node; IFN-α = interferon alpha; U-5HIAA = urinary 5-hydroxyindoleacetic acid (μmol/d); abd = abdomen; carbo = carboplatin; VP 16 = etoposide; TMZ = temozolomide; Cap = capecitabine; PP = pancreatic polypeptide (pmol/L).