PET Findings by Extent of CAD on Angiography
| Patients with*: | ||||||
| Parameter | All patients (n = 290)* | Normal coronary arteries (n = 24) | Nonobstructive CAD (n = 87) | 1- or 2-Vessel disease (n = 124) | High-risk CAD (n = 55) | P |
| Rest EDV (mL) | 95 (73–123) | 95 (71–143) | 99 (75–120) | 95 (72–117) | 93 (77–128) | 0.83 |
| Rest LVEF (%) | 58 (50–66) | 65.5 (56–70) | 57 (51–65) | 57 (50–66) | 59 (52–65) | 0.09 |
| ΔLVEF (%)† | 3 (0–7) | 6 (2–11) | 4 (0.5–8) | 3 (0–7) | 2 (−3–6) | 0.026 |
| TID index | 1.07 (0.98–1.20) | 1.01 (0.96–1.05) | 1.06 (0.96–1.05) | 1.09 (0.98–1.21) | 1.16 (1.06–1.27)‡ | 0.0016 |
| SRS (% of LV volume) | 0 (0–2.9) | 0 (0–2.9) | 0 (0–1.5) | 0 (0–2.9) | 0 (0–1.4) | 0.16 |
| SSS (% of LV volume) | 10.3 (5–16) | 5.9 (0–9) | 5.9 (0–10) | 13.2 (7–19) | 13.2 (9–26)‡ | <0.0001 |
| SDS (% of LV volume) | 8.8 (3–13) | 2.9 (0–6) | 4.4 (0–9) | 8.8 (6–15) | 13.2 (9–23)‡ | <0.0001 |
| Rest global MBF (mL/g/min) | 0.99 (0.75–1.27) | 1.13 (0.93–1.45) | 0.99 (0.81–1.25) | 0.97 (0.71–1.18) | 1.00 (0.75–1.30) | 0.04 |
| Rest global MBF corrected by rate–pressure product (mL/g/min) | 0.96 (0.76–1.27) | 1.19 (0.93–1.45) | 0.97 (0.77–1.29) | 0.92 (0.73–1.25) | 0.97 (0.74–1.31) | 0.011 |
| Stress global MBF (mL/g/min) | 1.63 (1.14–2.19) | 2.09 (1.69–2.93) | 1.72 (1.21–2.32) | 1.61 (1.14–2.12) | 1.44 (1.00–1.95) | 0.0002 |
| Global CFR | 1.62 (1.30–2.06) | 1.74 (1.31–2.48) | 1.68 (1.41–2.23) | 1.66 (1.30–2.06) | 1.48 (1.15–1.78)‡ | 0.0029 |
| Segments with CFR of <1.5 | 7 (2–11) | 5 (0–13) | 6 (1–10) | 6 (2–11) | 9 (5–14)‡ | 0.016 |
↵* Data (continuous variables) are presented as medians, with interquartile ranges in parentheses.
↵† Calculated as stress LVEF minus rest LVEF.
↵‡ High-risk CAD vs. 1- or 2-vessel-disease patients.
EDV = end-diastolic volume; LV = left ventricular; SRS = summed stress score; SSS = summed stress score; SDS = summed difference score.