TABLE 1

Schematics of Imaging and Therapy Regimen

GroupnDay 0Day 1Day 2Day 3
18F-alfatide II imaging (40 vs. 60 min) (U87MG, 7 mice; MDA-MB-435, 8 mice)
 115*
18F-FDG signal recovery validation (U87MG, 6 mice; MDA-MB-435, 8 mice)
 215
Therapy monitoring, U87MG
 3
  Control4
  Treated5§§
Therapy monitoring, MDA-MB-435
 4
  Control6
  Treated8
  • * 18F-alfatide II imaging.

  • 18F-FDG imaging.

  • 18F-alfatide II and 18F-FDG dual-tracer imaging.

  • § Doxorubicin treatment.

  • Abraxane treatment.