TABLE 3

Biodistribution of 111In-PC100 in Normal Mice

Time after injection (min)
Organ152060120240
Blood32.9 ± 4.0830.1 ± 0.4617.0 ± 5.995.75 ± 4.630.52 ± 0.491.58 ± 1.96
Intestine0.40 ± 0.050.46 ± 0.060.37 ± 0.160.28 ± 0.130.23 ± 0.100.59 ± 0.33
Kidney3.43 ± 0.503.51 ± 0.173.02 ± 0.962.28 ± 0.991.56 ± 0.383.39 ± 1.63
Liver6.34 ± 1.6712.5 ± 2.6628.1 ± 6.6547.2 ± 5.7553.8 ± 6.8546.5 ± 13.4
Stomach0.45 ± 0.140.56 ± 0.230.43 ± 0.140.40 ± 0.160.39 ± 0.210.44 ± 0.14
Spleen5.16 ± 2.7717.9 ± 3.20101 ± 32.6171 ± 69.4174 ± 68.3193 ± 53.7
Pancreas0.65 ± 0.140.66 ± 0.090.54 ± 0.250.32 ± 0.210.21 ± 0.190.84 ± 0.48
Lung18.9 ± 7.7611.8 ± 1.516.62 ± 1.913.48 ± 2.550.64 ± 0.502.66 ± 2.20
Heart4.33 ± 0.883.31 ± 1.002.08 ± 0.760.78 ± 0.630.19 ± 0.070.53 ± 0.54
  • Each value represents mean ± SD (percentage injected dose per gram of tissue, n = 4 or 5).