TABLE 4

Biodistribution of 111In-PC200 in Normal Mice

Time after injection (min)
Organ152060120240
Blood33.2 ± 4.0318.6 ± 5.016.83 ± 3.472.57 ± 1.331.10 ± 0.130.65 ± 0.10
Intestine0.36 ± 0.070.31 ± 0.050.27 ± 0.030.28 ± 0.070.32 ± 0.140.32 ± 0.09
Kidney3.35 ± 0.623.38 ± 0.514.81 ± 1.034.38 ± 0.754.72 ± 0.675.41 ± 1.02
Liver8.08 ± 2.3226.7 ± 8.3238.6 ± 4.1748.8 ± 3.3849.4 ± 6.1446.2 ± 7.84
Stomach0.54 ± 0.220.44 ± 0.160.44 ± 0.130.40 ± 0.140.33 ± 0.200.28 ± 0.11
Spleen10.0 ± 4.2449.4 ± 12.272.2 ± 15.5112 ± 30.3142 ± 43.8173 ± 76.2
Pancreas0.71 ± 0.270.58 ± 0.180.44 ± 0.140.43 ± 0.100.45 ± 0.150.38 ± 0.15
Lung20.8 ± 3.749.89 ± 1.794.20 ± 1.952.00 ± 0.741.62 ± 1.020.99 ± 0.24
Heart6.05 ± 2.532.95 ± 1.711.02 ± 0.390.56 ± 0.220.49 ± 0.130.33 ± 0.07
  • Each value represents mean ± SD (percentage injected dose per gram of tissue, n = 4 or 5).