44Sc-cm09 (% injected dose per gram tissue*) | ||||
Organ | 2 h after injection | 4 h after injection | 8 h after injection | 20 h after injection |
Blood | 3.74 ± 0.88 | 2.67 ± 0.35 | 1.77 ± 0.10 | 0.87 ± 0.08 |
Lung | 2.29 ± 0.42 | 1.84 ± 0.21 | 1.40 ± 0.10 | 0.90 ± 0.12 |
Spleen | 1.05 ± 0.19 | 0.90 ± 0.12 | 0.77 ± 0.01 | 0.70 ± 0.14 |
Kidneys | 19.21 ± 1.70 | 22.61 ± 4.52 | 21.30 ± 4.62 | 22.22 ± 1.94 |
Stomach | 1.19 ± 0.17 | 1.01 ± 0.06 | 0.81 ± 0.03 | 0.58 ± 0.02 |
Intestines | 0.59 ± 0.16 | 0.53 ± 0.09 | 0.38 ± 0.05 | 0.36 ± 0.12 |
Liver | 3.63 ± 0.19 | 3.12 ± 0.38 | 3.56 ± 0.55 | 2.31 ± 0.15 |
Salivary glands | 6.49 ± 0.52 | 6.48 ± 0.29 | 4.51 ± 0.53 | 3.48 ± 0.57 |
Muscle | 1.07 ± 0.03 | 1.30 ± 0.61 | 1.12 ± 0.37 | 0.76 ± 0.28 |
Bone | 0.98 ± 0.04 | 1.04 ± 0.16 | 0.92 ± 0.0.9 | 0.68 ± 0.05 |
Tumor | 8.37 ± 0.41 | 12.51 ± 1.74 | 12.43 ± 1.04 | 14.05 ± 2.29 |
Tumor to blood | 2.50 ± 0.59 | 3.79 ± 1.88 | 7.03 ± 0.64 | 16.07 ± 1.71 |
Tumor to liver | 2.31 ± 0.11 | 3.25 ± 1.62 | 3.34 ± 0.43 | 6.07 ± 0.72 |
Tumor to kidney | 0.44 ± 0.03 | 0.45 ± 0.23 | 0.59 ± 0.06 | 0.63 ± 0.07 |
↵* Values shown represent mean ± SD of data from 3 animals (n = 3) per cohort.